Article
Mapping determinants of human gene expression by regional and genome-wide association.
Nature - 27 Oct 2005
Cheung Vivian G, Spielman Richard S, Ewens Kathryn G, Weber Teresa M, Morley Michael, Burdick Joshua T
Abstract excerpt
To study the genetic basis of natural variation in gene expression, we previously carried out genome-wide linkage analysis and mapped the determinants of approximately 1,000 expression phenotypes. In the present study, we carried out association analysis with dense sets of single-nucleotide polymorphism (SNP) markers from the International HapMap Project. For 374 phenotypes, the association study was performed...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.