The genetics of regulatory variation in the human genome.

Abstract excerpt

The regulation of gene expression plays an important role in complex phenotypes, including disease in humans. For some genes, the genetic mechanisms influencing gene expression are well elucidated; however, it is unclear how applicable these results are to gene expression on a genome-wide level. Studies in model organisms and humans have clearly documented gene expression variation among individuals and shown...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Gene Expression Regulation
• Share to Genetic Variation
• Share to Genome, Human