Article
Global properties and functional complexity of human gene regulatory variation.
PLoS genetics - 1 May 2013
Gaffney Daniel J
Abstract excerpt
Identification and functional interpretation of gene regulatory variants is a major focus of modern genomics. The application of genetic mapping to molecular and cellular traits has enabled the detection of regulatory variation on genome-wide scales and revealed an enormous diversity of regulatory architecture in humans and other species. In this review I summarise the insights gained and questions raised by a...
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