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Article

Mitochondrial aldehyde dehydrogenase polymorphism is not associated with incidence of Alzheimer's disease.

International journal of geriatric psychiatry - 1 Nov 2005

Shin Ii-Seon, Stewart Robert, Kim Jae-Min, Kim Sung-Wan, Yang Su-Jin, Shin Hee-Young, Jung Jae-Sung, Yoon Jin-Sang

Abstract excerpt

BACKGROUND: The association between the mutant allele of mitochondrial aldehyde dehydrogenase (ALDH2*2) and Alzheimer's disease (AD) has been controversial and only so far investigated in cross-sectional studies. This study aimed to investigate the longitudinal association between ALDH2*2 and incidence of AD. METHODS: Of 592 participants aged 65 or over without dementia at baseline, 510 (86%) were re-evaluated...

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Source

Identifiers

PMID: 16250071
DOI: 10.1002/gps.1401

Genes

ALDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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