Article
Absence of association on aldehyde dehydrogenase 2 (ALDH2) polymorphism with Mongolian Alzheimer patients.
Neuroscience letters - 14 Jan 2010
Zhou Sirui, Huriletemuer, Wang Jing, Zhang Chunyu, Zhao Shigang, Wang De Sheng, Wang Binbin, Ma Xu
Abstract excerpt
The epsilon4 version of the Apolipoprotein E gene has been proved to be a risk factor for the development of Alzheimer's disease (AD). Furthermore, another gene mitochondrial aldehyde dehydrogenase (ALDH2) has also been proposed to be potentially associated with AD, based on its possible relations toward acetaldehyde accumulation which further damage brain cells. Yet this observation had been limited in several...
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