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Article

No genetic association between polymorphisms of heme oxygenase 1 and 2 and Alzheimer's disease in a Japanese population.

Dementia and geriatric cognitive disorders - 1 Jan 2009

Shibata Nobuto, Ohnuma Tohru, Baba Hajime, Arai Heii

Abstract excerpt

BACKGROUND/AIMS: Recently, it has been shown that the heme oxygenases HMOX1 and HMOX2 might play a role in the pathogenesis of Alzheimer's disease (AD). METHODS: To investigate whether there is any association between the HMOX1 and HMOX2 genes and AD, five single nucleotide polymorphisms (SNPs) in each gene were genotyped in 180 AD patients and 132 age-matched controls using TaqMan technology. RESULTS: Our study...

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Source

Identifiers

PMID: 19246912
DOI: 10.1159/000203891

Genes

HMOX1
HMOX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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