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Article

Mental retardation genes in drosophila: New approaches to understanding and treating developmental brain disorders.

Mental retardation and developmental disabilities research reviews - 1 Jan 2005

Restifo Linda L

Abstract excerpt

Drosophila melanogaster is emerging as a valuable genetic model system for the study of mental retardation (MR). MR genes are remarkably similar between humans and fruit flies. Cognitive behavioral assays can detect reductions in learning and memory in flies with mutations in MR genes. Neuroanatomical methods, including some at single-neuron resolution, are helping to reveal the cellular bases of faulty brain...

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PMID: 16240406
DOI: 10.1002/mrdd.20083

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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