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Article

Defective neuronal development in the mushroom bodies of Drosophila fragile X mental retardation 1 mutants.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 23 Jun 2004

Michel Carlos I, Kraft Robert, Restifo Linda L

Abstract excerpt

Fragile X mental retardation 1 (Fmr1) is a highly conserved gene with major roles in CNS structure and function. Its product, the RNA-binding protein FMRP, is believed to regulate translation of specific transcripts at postsynaptic sites in an activity-dependent manner. Hence, Fmr1 is central to the molecular mechanisms of synaptic plasticity required for normal neuronal maturation and cognitive ability....

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Identifiers

PMID: 15215302
DOI: 10.1523/JNEUROSCI.1102-04.2004
PMCID: PMC6729208

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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