Article
Defective neuronal development in the mushroom bodies of Drosophila fragile X mental retardation 1 mutants.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 23 Jun 2004
Michel Carlos I, Kraft Robert, Restifo Linda L
Abstract excerpt
Fragile X mental retardation 1 (Fmr1) is a highly conserved gene with major roles in CNS structure and function. Its product, the RNA-binding protein FMRP, is believed to regulate translation of specific transcripts at postsynaptic sites in an activity-dependent manner. Hence, Fmr1 is central to...
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