Article
Association of linear plasmid 28-1 with an arthritic phenotype of Borrelia burgdorferi.
Infection and immunity - 1 Nov 2005
Xu Qilong, Seemanapalli Sunita V, Lomax Larry, McShan Kristy, Li Xin, Fikrig Erol, Liang Fang Ting
Abstract excerpt
Borrelia burgdorferi, the Lyme disease spirochete, has a genome comprised of a linear chromosome and up to 21 plasmids. Loss of plasmids is associated with decreased infectivity and pathogenicity. Sixteen transformants were generated by transforming the noninfectious clone 5A13 with the recombinant plasmid pBBE22. The transformants were classified into nine groups based on plasmid content analysis. An infectivity...
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