Article
Plasmid requirements for infection of ticks by Borrelia burgdorferi.
Vector borne and zoonotic diseases (Larchmont, N.Y.) - 1 Jan 2005
Strother Keith O, Broadwater Anne, De Silva Aravinda
Abstract excerpt
Borrelia burgdorferi strain B31 MI commonly loses one or more of its complement of 21 extrachromosomal plasmids during normal handling procedures and during genetic manipulations. Certain plasmid losses cause an inability or reduction in the ability of spirochetes to infect mice. In the current study, nine strains of spirochetes with varying plasmid profiles were used to identify plasmids necessary for nymphal...
Topics
- Animals
- Arachnid Vectors
- Borrelia burgdorferi
- Female
- Lyme Disease
- Mice
- Mice, Inbred C3H
- Mutation
- Nymph
- Plasmids
- Ticks