Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Altered Murine Tissue Colonization by Borrelia burgdorferi following Targeted Deletion of Linear Plasmid 17-Carried Genes

22 Feb 2012

Abstract excerpt

The causative agent of Lyme disease, Borrelia burgdorferi, possesses a segmented genome comprised of a single linear chromosome and upwards of 23 linear and circular plasmids. Much of what is known about plasmid-borne genes comes from studying laboratory clones that have spontaneously lost one or more plasmids during in vitro passage. Some plasmids, including the linear plasmid lp17, are never or rarely reported...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Vector-Borne Animal Diseases
Share to Vector-borne infectious diseases
Share to Viral Infections and Vectors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22354033
DOI: 10.1128/iai.05984-11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Altered Murine Tissue Colonization by Borrelia burgdorferi following Targeted Deletion of Linear Plasmid 17-Carried GenesPMID 22354033Read ↗

A small intergenic region of lp17 is required for evasion of adaptive immunity and induction of pathology by the Lyme disease spirocheteSemantic proximity Read ↗

Decreased infectivity in Borrelia burgdorferi strain B31 is associated with loss of linear plasmid 25 or 28-1.Semantic proximity Read ↗

Association of linear plasmid 28-1 with an arthritic phenotype of Borrelia burgdorferi.Semantic proximity Read ↗

Experimental assessment of the roles of linear plasmids lp25 and lp28-1 of Borrelia burgdorferi throughout the infectious cycle.Semantic proximity Read ↗

In Vivo Expression Technology Identifies a Novel Virulence Factor Critical for Borrelia burgdorferi Persistence in MiceSemantic proximity Read ↗

Role of Borrelia burgdorferi linear plasmid 25 in infection of Ixodes scapularis ticks.Semantic proximity Read ↗

bptA ( bbe16 ) is essential for the persistence of the Lyme disease spirochete, Borrelia burgdorferi , in its natural tick vectorSemantic proximity Read ↗

The absence of linear plasmid 25 or 28-1 of Borrelia burgdorferi dramatically alters the kinetics of experimental infection via distinct mechanisms.Semantic proximity Read ↗

BBB07 contributes to, but is not essential for, Borrelia burgdorferi infection in mice.Semantic proximity Read ↗

Plasmid requirements for infection of ticks by Borrelia burgdorferi.Semantic proximity Read ↗

Competitive advantage of Borrelia burgdorferi with outer surface protein BBA03 during tick-mediated infection of the mammalian host.Semantic proximity Read ↗

An lp17-encoded small non-coding RNA with a potential regulatory role in mammalian host adaptation by the Lyme disease spirocheteSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.