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Correlation of plasmids with infectivity of Borrelia burgdorferi sensu stricto type strain B31

1 Sept 1996

Abstract excerpt

The correlation of plasmid profiles with infectivity was investigated by using five clones of Borrelia burgdorferi sensu stricto strain B31 (ATCC 35210). Plasmid profiles were determined by pulsed-field and two-dimensional gel electrophoresis. The 50% infectious dose (ID50) in hamsters was determined. The ID50 of the clone that possessed a full complement of eight linear and three circular plasmids was 10(3)...

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PMID: 8751941
DOI: 10.1128/iai.64.9.3870-3876.1996

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