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Article

Structure and dynamics of zymogen human blood coagulation factor X.

Biophysical journal - 1 Mar 2002

Venkateswarlu Divi, Perera Lalith, Darden Tom, Pedersen Lee G

Abstract excerpt

The solution structure and dynamics of the human coagulation factor X (FX) have been investigated to understand the key structural elements in the zymogenic form that participates in the activation process. The model was constructed based on the 2.3-A-resolution x-ray crystallographic structure of active-site inhibited human FXa (PDB:1XKA). The missing gamma-carboxyglutamic acid (GLA) and part of epidermal growth...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 11867437
DOI: 10.1016/S0006-3495(02)75476-3
PMCID: PMC1301923

Genes

GLA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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