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Article

Presenilin-2 polymorphisms and risk of sporadic AD: evidence from a meta-analysis.

Gene - 25 Jul 2012

Chen Chunhai, Zhou Zhou, Li Maoquan, Qu Mingyue, Ma Qinlong, Zhong Min, Zhang Yanwen, Yu Zhengping

Abstract excerpt

Association studies of presenilin-2 (PSEN2) polymorphisms and sporadic Alzheimer's disease (AD) have yielded inconsistent results, possibly because single studies often lack sufficient statistical power. In this study, we performed a meta-analysis to evaluate the association of the two most extensively studied PSEN2 polymorphisms, rs8383 and 5'indel, with the risk of sporadic AD. We systematically reviewed...

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Source

Identifiers

PMID: 22580083
DOI: 10.1016/j.gene.2012.05.005

Genes

PSEN2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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