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Article

Two polymorphisms of presenilin-2 gene (PSEN2) 5' regulatory region are not associated with Alzheimer's disease (AD) in the Polish population.

Journal of neural transmission (Vienna, Austria : 1996) - 1 Jan 2008

Gacia M, Safranow K, Gabryelewicz T, Styczyńska M, Pepłońska B, Dziedziejko V, Jakubowska K, Chlubek D, Zekanowski C, Barcikowska M

Abstract excerpt

Presenilin 2 gene (PSEN2) is one of the causative genes for familial Alzheimer's disease. A delA polymorphism located in PSEN2 promoter was proposed to be a risk factor for early-onset AD. We examined association between AD and PSEN2 polymorphisms located in two 5'UTR regions in group of 217 late-onset AD patients, 109 mild cognitive impairment patients, and 225 non-demented control subjects. No significant...

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Source

Identifiers

PMID: 18087668
DOI: 10.1007/s00702-007-0846-x

Genes

PSEN2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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