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Article

CREB and phospho-CREB interact with RFX5 and CIITA to regulate MHC class II genes.

Molecular immunology - 1 Feb 2007

Lochamy Jonathan, Rogers Edward M, Boss Jeremy M

Abstract excerpt

Major histocompatibility class II (MHC-II) genes are coordinately regulated by conserved, upstream promoter elements that are bound cooperatively by cyclic AMP response element binding protein (CREB), regulatory factor X (RFX), and nuclear factor Y (NF-Y). These DNA-binding proteins serve as a scaffold for the transcriptional coactivator class II transactivator (CIITA). To determine how CREB interacts with RFX...

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Source

Identifiers

PMID: 16730065
DOI: 10.1016/j.molimm.2006.04.004

Genes

CIITA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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