Article
COL6A1, the candidate gene for ossification of the posterior longitudinal ligament, is associated with diffuse idiopathic skeletal hyperostosis in Japanese.
Spine - 15 Oct 2005
Tsukahara So, Miyazawa Nobuhiko, Akagawa Hiroyuki, Forejtova Sarka, Pavelka Karel, Tanaka Toshihiro, Toh Satoshi, Tajima Atsushi, Akiyama Iwao, Inoue Ituro
Abstract excerpt
STUDY DESIGN: Genetic screening of collagen 6A1 gene (COL6A1) in patients with diffuse idiopathic skeletal hyperostosis (DISH) recruited in Japan and the Czech Republic. OBJECTIVE: To investigate allelic associations between DISH and nucleotide variants of COL6A1. SUMMARY OF BACKGROUND DATA: DISH is a skeletal hyperostotic disease characterized by ligamentous ossification of the anterolateral side of the spine....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.