Article
A new single nucleotide polymorphism affects the predisposition to thoracic ossification of the posterior longitudinal ligament.
Journal of orthopaedic surgery and research - 12 Dec 2019
Wang Peng, Teng Ze, Liu Xiaoguang, Liu Xiao, Kong Chao, Lu Shibao
Abstract excerpt
BACKGROUND: Thoracic ossification of the posterior longitudinal ligament (T-OPLL) is one of the common factors that cause thoracic spinal stenosis, which results in intractable myelopathy and radiculopathy. Our previous study first reported rs201153092A site mutation in the collagen 6A1 (COL6A1) gene as a potentially pathogenic locus for T-OPLL. We aimed to determine whether the rs201153092A site mutation causes...
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