Article
A Multicenter Allelic Analysis of Diffuse Idiopathic Skeletal Hyperostosis: Nature Versus Nurture?
Neurosurgery - 1 Aug 2023
Zervos Thomas M, Jago Silvienne Sint, Erwood Matthew S, Basheer Azam, Lee Ian Y, Lubin Farah D, Schultz Lonni, Walters Beverly C
Abstract excerpt
BACKGROUND: Diffuse idiopathic skeletal hyperostosis (DISH) is an incompletely defined disease process with no known unifying pathophysiological mechanism. OBJECTIVE: To our knowledge, no genetic studies have been performed in a North American population. To summarize genetic findings from previous studies and to comprehensively test for these associations in a novel and diverse, multi-institutional population....
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