Article
Association of IL17RC and COL6A1 genetic polymorphisms with susceptibility to ossification of the thoracic posterior longitudinal ligament in Chinese patients.
Journal of orthopaedic surgery and research - 15 May 2018
Wang Peng, Liu Xiao, Zhu Bin, Ma Yunlong, Yong Lei, Teng Ze, Liang Chen, He Guanping, Liu Xiaoguang
Abstract excerpt
BACKGROUND: In our previous whole-genome sequencing study of 30 unrelated northern Chinese Han patients, we identified six single nucleotide polymorphisms (SNPs) in the interleukin 17 receptor C (IL17RC) and collagen type VI α1 chain (COL6A1) genes that were potentially associated with thoracic ossification of the posterior longitudinal ligament (T-OPLL). To determine whether these six SNPs are associated with...
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