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Article

Steps for Shigella Gatekeeper Protein MxiC Function in Hierarchical Type III Secretion Regulation.

The Journal of biological chemistry - 3 Feb 2017

Roehrich A Dorothea, Bordignon Enrica, Mode Selma, Shen Da-Kang, Liu Xia, Pain Maria, Murillo Isabel, Martinez-Argudo Isabel, Sessions Richard B, Blocker Ariel J

Abstract excerpt

Type III secretion systems are complex nanomachines used for injection of proteins from Gram-negative bacteria into eukaryotic cells. Although they are assembled when the environmental conditions are appropriate, they only start secreting upon contact with a host cell. Secretion is hierarchical. First, the pore-forming translocators are released. Second, effector proteins are injected. Hierarchy between these...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27974466
DOI: 10.1074/jbc.M116.746826
PMCID: PMC5290946

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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