Article
Helical packing of needles from functionally altered Shigella type III secretion systems.
Journal of molecular biology - 25 Nov 2005
Cordes Frank S, Daniell Sarah, Kenjale Roma, Saurya Saroj, Picking Wendy L, Picking William D, Booy Frank, Lea Susan M, Blocker Ariel
Abstract excerpt
Gram-negative bacteria commonly interact with eukaryotic host cells using type III secretion systems (TTSSs or secretons), which comprise cytoplasmic, transmembrane and extracellular domains. The extracellular domain is a hollow needle-like structure protruding 60 nm beyond the bacterial surface. The TTSS is activated to transfer bacterial proteins directly into a host cell only upon physical contact with the...
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