Article
Identification of the MxiH needle protein residues responsible for anchoring invasion plasmid antigen D to the type III secretion needle tip.
The Journal of biological chemistry - 2 Nov 2007
Zhang Lingling, Wang Yu, Olive Andrew J, Smith Nathan D, Picking William D, De Guzman Roberto N, Picking Wendy L
Abstract excerpt
The pathogenesis of Shigella flexneri requires a functional type III secretion apparatus to serve as a conduit for injecting host-altering effector proteins into the membrane and cytoplasm of the targeted cell. The type III secretion apparatus is composed of a basal body and an exposed needle tha...
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