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Article

SLAM-associated protein as a potential negative regulator in Trk signaling.

The Journal of biological chemistry - 16 Dec 2005

Lo Kin Yip, Chin Wing Hong, Ng Yu Pong, Cheng Albert W, Cheung Zelda H, Ip Nancy Y

Abstract excerpt

Neurotrophin signaling plays important roles in regulating the survival, differentiation, and maintenance of neurons in the nervous system. Binding of neurotrophins to their cognate receptors Trks induces transactivation and phosphorylation of the receptor at several tyrosine residues. These phosphorylated tyrosine residues then serve as crucial docking sites for adaptor proteins containing a Src homology 2 or...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16223723
DOI: 10.1074/jbc.M506554200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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