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Article

Csk-homologous kinase interacts with SHPS-1 and enhances neurite outgrowth of PC12 cells.

Journal of neurochemistry - 1 Apr 2008

Mitsuhashi Hiroaki, Futai Eugene, Sasagawa Noboru, Hayashi Yukiko, Nishino Ichizo, Ishiura Shoichi

Abstract excerpt

SHPS-1 is an immunoglobulin superfamily protein with four immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in its cytoplasmic region. Various neurotrophic factors induce the tyrosine phosphorylation of SHPS-1 and the association of SHPS-1 with the protein tyrosine phosphatase SHP-2. Using a yeast two-hybrid screen, we identified a protein tyrosine kinase, Csk-homologous kinase (CHK), as an...

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Source

Identifiers

PMID: 17999719
DOI: 10.1111/j.1471-4159.2007.05121.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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