Article
Src-like adaptor protein (Slap) is a negative regulator of mitogenesis.
Current biology : CB - 27 Aug 1998
Roche S, Alonso G, Kazlauskas A, Dixit V M, Courtneidge S A, Pandey A
Abstract excerpt
The Src-like adaptor protein (Slap) is a recently identified adaptor protein containing Src homology 3 (SH3) and SH2 domains. Slap is found in a wide range of cell types and was shown to interact with the Eck receptor tyrosine kinase in a yeast two-hybrid interaction screen [1]. Here, we found th...
Topics
- 3T3 Cells
- Adaptor Proteins, Signal Transducing
- Adaptor Proteins, Vesicular Transport
- Animals
- Binding, Competitive
- Cell Division
- DNA
- Fibroblasts
- GRB2 Adaptor Protein
- Mice
- Mutation
- Phosphorylation
- Proteins
- Proto-Oncogene Proteins pp60(c-src)
- Receptors, Platelet-Derived Growth Factor
- Recombinant Fusion Proteins
- Shc Signaling Adaptor Proteins
- Src Homology 2 Domain-Containing, Transforming Protein 1