Single nucleotide polymorphisms detection based on DNA microarray technology: HLA as a model.

doi:10.1016/j.autrev.2005.04.011

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Article

Single nucleotide polymorphisms detection based on DNA microarray technology: HLA as a model.

Autoimmunity reviews - 1 Nov 2005

Palmisano Giulio Lelio, Delfino Laura, Fiore Monica, Longo Anna, Ferrara Giovanni Battista

Abstract excerpt

The significance of DNA variations among individuals, including single nucleotide polymorphisms (SNPs) and/or genome nucleotide mutations as well as to their detection by using new technology, will improve and facilitate the knowledge of each gene sequence. Microarray may provide information about thousands of gene simultaneously, leading to a more rapid and accurate genotyping. In this view, we developed a new...

Topics

Alleles
DNA
HLA Antigens
Histocompatibility Testing
Humans
Nucleic Acid Hybridization
Oligonucleotide Array Sequence Analysis
Polymorphism, Single Nucleotide

Source

Open in PubMed

Identifiers

PMID: 16214087
DOI: 10.1016/j.autrev.2005.04.011

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