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No evidence of correlation between the single nucleotide polymorphism of DNMT3B promoter and gastric cancer risk in a Japanese population.

Oncology reports - 1 Nov 2005

Aung Phyu Phyu, Matsumura Shunji, Kuraoka Kazuya, Kunimitsu Kyoko, Yoshida Kazuhiro, Matsusaki Keisuke, Nakayama Hirofumi, Yasui Wataru

Abstract excerpt

DNA methylation is a major epigenetic modification in humans, and aberrant DNA methylation may play an important role in the development of various cancers through the silencing of some tumor suppressor genes. DNMT3B is required for the establishment and maintenance of genomic methylation patterns. The -149 C/T single nucleotide polymorphism (SNP) in the promoter of DNMT3B has been identified. This SNP influences...

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PMID: 16211278

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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