Article
Single nucleotide polymorphism in DNA methyltransferase 3B promoter and its association with gastric cardiac adenocarcinoma in North China.
World journal of gastroenterology - 21 Jun 2005
Wang Yi-Min, Wang Rui, Wen Deng-Gui, Li Yan, Guo Wei, Wang Na, Wei Li-Zhen, He Yu-Tong, Chen Zhi-Feng, Zhang Xiu-Feng, Zhang Jian-Hui
Abstract excerpt
AIM: To investigate the association between single nucleotide polymorphism (SNP) in promoter of the DNA methyltransferase 3B (DNMT3B) gene and risk for development and lymphatic metastasis of gastric cardiac adenocarcinoma (GCA). METHODS: The hospital based case-control study included 212 GCA patients and 294 control subjects without overt cancer. The DNMT3B SNP was genotyped by PCR and restriction fragment...
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