Article
Altered expression of mitogen-activated protein kinases in a rat model of experimental hepatocellular carcinoma.
Hepatology (Baltimore, Md.) - 1 Dec 1997
McKillop I H, Schmidt C M, Cahill P A, Sitzmann J V
Abstract excerpt
The mitogen-activated protein kinase (MAPK) cascade acts as a focal point for signal transduction following activation of both G-protein-linked and tyrosine kinase growth factor receptors. A common intermediate between both of these diverse receptor subtypes includes the small guanosine triphosph...
Topics
- Animals
- Blotting, Western
- Calcium-Calmodulin-Dependent Protein Kinases
- Carcinoma, Hepatocellular
- Liver Neoplasms
- MAP Kinase Kinase 1
- MAP Kinase Kinase 2
- Male
- Mitogen-Activated Protein Kinase Kinases
- Mitogen-Activated Protein Kinases
- Mutation
- Nerve Tissue Proteins
- Phosphorylation
- Proliferating Cell Nuclear Antigen
- Protein Serine-Threonine Kinases
- Protein-Tyrosine Kinases
- Proto-Oncogene Proteins p21(ras)
- Rats