Article
Establishment of a growth hormone responsive chondrogenic cell line from fetal rat tibia.
Molecular and cellular endocrinology - 1 Feb 1993
Ohlsson C, Nilsson A, Swolin D, Isaksson O G, Lindahl A
Abstract excerpt
Reproducible effects of growth hormone (GH) on primary isolated cells in monolayer are highly dependent on the culture conditions and/or the fraction of GH responsive cells. To study the effect of GH at the cellular level, a homogenous cell line with both GH responsiveness and chondrogenic proper...
Topics
- Animals
- Blotting, Northern
- Cartilage
- Cell Division
- Clone Cells
- Collagen
- DNA
- Growth Hormone
- Immunohistochemistry
- Insulin-Like Growth Factor I
- Karyotyping
- Phenotype
- RNA
- Rats
- Rats, Sprague-Dawley
- Receptors, Somatotropin
- Tibia