Article
Terminal differentiation of chondrocytes is arrested at distinct stages identified by their expression repertoire of marker genes.
Matrix biology : journal of the International Society for Matrix Biology - 1 Oct 1998
Szuts V, Möllers U, Bittner K, Schürmann G, Muratoglu S, Deák F, Kiss I, Bruckner P
Abstract excerpt
During endochondral bone formation, cells in the emerging cartilaginous model transit through a cascade of several chondrocyte differentiation stages, each characterized by a specific expression repertoire of matrix macromolecules, until, as a final step, the hypertrophic cartilage is replaced by...
Topics
- Animals
- Cell Differentiation
- Cells, Cultured
- Chick Embryo
- Chondrocytes
- Fibroblast Growth Factor 2
- Genetic Markers
- Hedgehog Proteins
- Insulin
- Phenotype
- Proteins
- RNA
- Trans-Activators
- Transforming Growth Factor beta