Article

Insulin-Like Growth Factor Binding Protein 5: A Novel Regulator of Early Osteogenic Differentiation of hMSCs

2021-02-19

Abstract excerpt

<title>Abstract</title> <p>Insulin-like growth factor binding protein 5 (IGFBP5) is broadly bioactive, but its role in osteogenic differentiation of human bone marrow-derived mesenchymal stem cells (hMSCs) remains to be clarified. Herein, we determined that IGFBP5 expression was markedly increased during the early osteogenic differentiation of hMSCs. We then overexpressed and knocked down this gene in hMSCs and e...

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Literature Corpus work: 9ffba7d2-7152-5513-ae6b-6f7e824486a6
DOI: 10.21203/rs.3.rs-212703/v1

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