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Article

Oligonucleotide chip for the diagnosis of HNF-1 alpha mutations.

Biosensors & bioelectronics - 15 Oct 2005

Park Hyun Gyu, Ham Hyun Ok, Kim Kyung Hee, Huh Nam

Abstract excerpt

Mutations in HNF-1 alpha cause maturity-onset diabetes of the young (MODY) type 3, which is the most prevalent MODY subtype in most countries. In the present study, we investigated an oligonucleotide microchip for the detection of the known HNF-1 alpha mutations. We first optimized the coupling chemistries for covalent immobilization of allele-specific oligonucleotides on aldehyde (CHO)- and thiocyanate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16202877
DOI: 10.1016/j.bios.2004.12.022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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