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An improved gel-based DNA microarray method for detecting single nucleotide mismatch.

Electrophoresis - 1 Oct 2006

Xiao Peng Feng, Cheng Lu, Wan Yuan, Sun Bei Li, Chen Zao Zao, Zhang Sheng You, Zhang Chung Ziu, Zhou Guo Hua, Lu Zu Hong

Abstract excerpt

3-D polyacrylamide gel-based DNA microarray platforms provide a high capacity for nucleic acids immobilization and a solution-mimicking environment for hybridization. However, several technological bottlenecks still remain in these platforms, such as difficult microarray preparation and high fluorescent background, which limit their application. In this study, two new approaches have been developed to improve the...

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Share to DNA Mutational Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Source

Identifiers

PMID: 16960844
DOI: 10.1002/elps.200500918

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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