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Article

Single-nucleotide polymorphism analysis by hybridization protection assay on solid support.

Analytical biochemistry - 1 Aug 2002

Goto Susumu, Takahashi Aki, Kamisango Keiichi, Matsubara Koichi

Abstract excerpt

The clinical need for high-throughput typing methods of single-nucleotide polymorphisms (SNPs) has been increasing. Conventional methods do not perform well enough in terms of speed and accuracy to process a large number of samples, as in clinical testing. We report a new DNA microarray method that uses hybridization protection assay (HPA) by acridinium-ester-labeled DNA probes. Probes were immobilized on the...

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PMID: 12137775
DOI: 10.1016/s0003-2697(02)00019-2

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ALDH2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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