Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A regulatory polymorphism in promoter region of TNFR1 gene is associated with Kawasaki disease in Chinese individuals.

Human immunology - 1 May 2011

Wang Guo-Bing, Li Cheng-Rong, Yang Jun, Wen Peng-Qiang, Jia Shi-Lei

Abstract excerpt

Tumor necrosis factor (TNF) and the TNF receptor superfamily (TNF-TNFR) plays very important roles in the pathogenesis of Kawasaki disease (KD) by leukocyte recruitment, upregulation of matrix-degrading enzymes and proinflammatory cytokines. This study aims to investigate whether potential polymorphisms in TNF receptor superfamily member 1A gene (TNFR1) are associated with KD and its effects on transcriptions...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to China
Share to Genetic Association Studies
Share to High-Throughput Nucleotide Sequencing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mucocutaneous Lymph Node Syndrome

Share to Promoter Regions, Genetic

Share to Receptors, Tumor Necrosis Factor, Type I

Share to Regulatory Sequences, Nucleic Acid

Share to Transcriptional Activation

Source

Identifiers

PMID: 21315128
DOI: 10.1016/j.humimm.2011.02.004

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A regulatory polymorphism in promoter region of TNFR1 gene is associated with Kawasaki disease in Chinese individuals.PMID 21315128Read ↗

Association of TNF-α rs1800629, CASP3 rs72689236 and FCGR2A rs1801274 Polymorphisms with Susceptibility to Kawasaki Disease: A Comprehensive Meta-Analysis.Semantic proximity Read ↗

Pro-inflammatory cytokine single nucleotide polymorphisms in Kawasaki disease.Semantic proximity Read ↗

The Roles of Genetic Factors in Kawasaki Disease: A Systematic Review and Meta-analysis of Genetic Association Studies.Semantic proximity Read ↗

Promoter polymorphism (rs3755724, -55C/T) of tissue inhibitor of metalloproteinase 4 (TIMP4) as a risk factor for Kawasaki disease with coronary artery lesions in a Korean population.Semantic proximity Read ↗

Association analysis of single nucleotide polymorphisms of proinflammatory cytokine and their receptors genes with rheumatoid arthritis in northwest Chinese Han population.Semantic proximity Read ↗

[Research advances in genetic polymorphisms in Kawasaki disease].Semantic proximity Read ↗

In silico analysis of missense SNPs in TNFR1a and their possible therapeutic or pathogenic role in immune diseases.Semantic proximity Read ↗

Polymorphisms of transforming growth factor-β signaling pathway and Kawasaki disease in the Taiwanese population.Semantic proximity Read ↗

The roles of Ca2+/NFAT signaling genes in Kawasaki disease: single- and multiple-risk genetic variants.Semantic proximity Read ↗

Identification of novel susceptibility Loci for kawasaki disease in a Han chinese population by a genome-wide association study.Semantic proximity Read ↗

Identification of single nucleotide polymorphisms in the tumor necrosis factor (TNF) and TNF receptor superfamily in the Korean population.Semantic proximity Read ↗

A systematic review and meta-analysis of tumor necrosis factor α-308 polymorphism and Kawasaki disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.