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Article

Promoter polymorphisms in IL-6 gene influence pro-inflammatory cytokines for the risk of osteoarthritis.

Cytokine - 1 Mar 2020

Singh Monica, Mastana Sarabjit, Singh Surinderpal, Juneja Pawan Kumar, Kaur Taranpal, Singh Puneetpal

Abstract excerpt

BACKGROUND: Interleukin-6 (IL-6) gene regulates IL-6 levels, interplay of which has been found to influence pathophysiology of osteoarthritis (OA). Polymorphism within promoter region of IL-6 gene and its association with plasma levels of pro-inflammatory cytokines; IL-6, interleukin 1-beta (IL-1β) and tumor necrosis factor-alpha (TNF-α) remained to be investigated in Punjab region of India, where OA is highly...

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Identifiers

PMID: 31951965
DOI: 10.1016/j.cyto.2020.154985

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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