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Article

cAMP response element binding protein (CREB) overexpression CREB has been described as critical for leukemia progression

1 Oct 2007

Abstract excerpt

CREB has been described as critical for leukemia progress. We investigated CREB expression in ALL and AML pediatric patients. CREB protein was significantly high (p<0.001) at diagnosis but not during remission. This study underlines the role of CREB in leukemia and suggests new insights into the transformation process.

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Identifiers

PMID: 18024382
DOI: 10.3324/haematol.11122

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