Article
IgG Fc receptor polymorphisms and association with autoimmune disease.
European journal of immunology - 1 Oct 2005
Andrén Maria, Johanneson Bo, Alarcón-Riquelme Marta E, Kleinau Sandra
Abstract excerpt
The aim of this study was to investigate whether a genetic polymorphism of Fc gammaRIII exists in mice, which could explain the different susceptibility to pathogenic IgG anti-collagen type II (CII) antibodies in mice carrying the collagen-induced arthritis (CIA)-susceptible H-2q haplotype. The gene for Fc gammaRIII was sequenced in 11 common mouse strains, and the results revealed three different haplotypes of...
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