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Article

Genetic control of susceptibility to collagen-induced arthritis in T cell receptor beta-chain transgenic mice.

Arthritis and rheumatism - 1 Feb 1998

Mori L, de Libero G

Abstract excerpt

OBJECTIVE: To study the genes in the mouse background which predispose to the development of collagen-induced arthritis (CIA). METHODS: T cell receptor beta transgenic (TCRbetaL) mice that have a T cell repertoire that predisposes to the development of CIA were used. Classic genetic studies and microsatellite gene mapping were done in (SWR-betaL x DBA/1)F2 hybrid mice. RESULTS: Besides TCRbeta, major...

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PMID: 9485083
DOI: 10.1002/1529-0131(199802)41:2<256::AID-ART9>3.0.CO;2-E

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