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Article

The influence of NAT2 genotypes on the plasma concentration of isoniazid and acetylisoniazid in Chinese pulmonary tuberculosis patients.

Clinica chimica acta; international journal of clinical chemistry - 1 Mar 2006

Chen Bing, Li Jin-Heng, Xu Yi-Min, Wang Jie, Cao Xiao-Mei

Abstract excerpt

BACKGROUND: Isoniazid (INH) is widely used in the therapy of tuberculosis. Poor metabolizer (PM) of the NAT2 is an important reason of inter-individual difference of the plasma INH concentration. We studied the relationship between NAT2 genotype and INH and its metabolite acetylisoniazid (AcINH) concentration in Chinese people. METHOD: Forty-six tuberculosis patients were enrolled in the study. Each patient took...

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Source

Identifiers

PMID: 16182272
DOI: 10.1016/j.cca.2005.08.012

Genes

NAT2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The influence of NAT2 genotypes on the plasma concentration of isoniazid and acetylisoniazid in Chinese pulmonary tuberculosis patients.PMID 16182272Read ↗

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