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Article

Bloom syndrome ortholog HIM-6 maintains genomic stability in C. elegans.

Mechanisms of ageing and development - 1 Dec 2005

Grabowski Melissa M, Svrzikapa Nenad, Tissenbaum Heidi A

Abstract excerpt

Bloom syndrome is caused by mutation of the Bloom helicase (BLM), a member of the RecQ helicase family. Loss of BLM function results in genomic instability that causes a high incidence of cancer. It has been demonstrated that BLM is important for maintaining genomic stability by playing a role in DNA recombination and repair; however, the exact function of BLM is not clearly understood. To determine the mechanism...

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Source

Identifiers

PMID: 16181657
DOI: 10.1016/j.mad.2005.08.005

Genes

BLM

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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