Frequent alteration of <i> p16 ^INK4a /p14 ^ARF </i> and <i>p53</i> pathways in the round cell component of myxoid/round cell liposarcoma: <i>p53</i> gene alterations and reduced p14 ^ARF expression both correlate with poor prognosis

Abstract excerpt

In myxoid/round cell liposarcoma (MLS/RCLS), the presence of a round cell (RC) component has been reported to correlate with a worse prognosis for the patients. However, little is known about the molecular genetic differences between conventional myxoid (MX) components and RC components in this tumour. The aim of this study was to investigate the possible implications of molecular alterations of G1 to S-phase...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Bone Tumor Diagnosis and Treatments
• Share to Ear and Head Tumors