Article
Highly aggressive behavior of malignant rhabdoid tumor: a special reference to SMARCB1/INI1 gene alterations using molecular genetic analysis including quantitative real-time PCR.
Journal of cancer research and clinical oncology - 1 Nov 2007
Kohashi Kenichi, Oda Yoshinao, Yamamoto Hidetaka, Tamiya Sadafumi, Izumi Teiyu, Ohta Shigeru, Taguchi Tomoaki, Suita Sachiyo, Tsuneyoshi Masazumi
Abstract excerpt
PURPOSE: SMARCB1/INI1, which negatively regulates cell cycle progression from G0/G1 into the S-phase via the p16INK4a-RB-E2F pathway, has been reported to be inactivated homozygously by deletion and/or mutations in malignant rhabdoid tumor (MRT). In the current study, we investigated the alterati...
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