Article
Induction of SAP7 correlates with virulence in an intravenous infection model of candidiasis but not in a vaginal infection model in mice.
Infection and immunity - 1 Oct 2005
Taylor Brad N, Hannemann Holger, Sehnal Miriam, Biesemeier Antje, Schweizer Anja, Röllinghoff Martin, Schröppel Klaus
Abstract excerpt
SAP7 of Candida albicans is induced after vaginal infection of mice. Conversely, virulence during vaginal infection was not affected in a Deltasap7/Deltasap7 mutant strain. Only a partial virulence phenotype was detectable after intravenous injection. In conclusion, SAP7 expression does not correlate with C. albicans virulence in mice.
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