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Profile of <i>Candida albicans-</i> Secreted Aspartic Proteinase Elicited during Vaginal Infection

24 Feb 2005

Abstract excerpt

Vaginal infections caused by the opportunistic yeast Candida albicans are a significant problem in women of child-bearing age. Several factors are recognized as playing a crucial role in the pathogenesis of superficial candidiasis; these factors include hyphal formation, phenotypic switching, and the expression of virulence factors, including a 10-member family of secreted aspartic proteinases. In the present...

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PMID: 15731084
DOI: 10.1128/iai.73.3.1828-1835.2005

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