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Article

Limited role of secreted aspartyl proteinases Sap1 to Sap6 in Candida albicans virulence and host immune response in murine hematogenously disseminated candidiasis.

Infection and immunity - 1 Nov 2010

Correia Alexandra, Lermann Ulrich, Teixeira Luzia, Cerca Filipe, Botelho Sofia, da Costa Rui M Gil, Sampaio Paula, Gärtner Fátima, Morschhäuser Joachim, Vilanova Manuel, Pais Célia

Abstract excerpt

Candida albicans secreted aspartyl proteinases (Saps) are considered virulence-associated factors. Several members of the Sap family were claimed to play a significant role in the progression of candidiasis established by the hematogenous route. This assumption was based on the observed attenuated virulence of sap-null mutant strains. However, the exclusive contribution of SAP genes to their attenuated phenotype...

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Identifiers

PMID: 20679440
DOI: 10.1128/IAI.00248-10
PMCID: PMC2976357

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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