Article
Expression of seven members of the gene family encoding secretory aspartyl proteinases in Candida albicans.
Molecular microbiology - 1 Oct 1994
Hube B, Monod M, Schofield D A, Brown A J, Gow N A
Abstract excerpt
The opportunistic fungal pathogen Candida albicans produces secretory aspartyl proteinases, which are believed to be virulence factors in infection. We have studied the in vitro expression of seven known members of the SAP gene family in a range of strains and serotypes by Northern analysis. SAP1...
Topics
- Amino Acid Sequence
- Aspartic Acid Endopeptidases
- Blotting, Northern
- Candida albicans
- Gene Expression
- Gene Expression Regulation, Enzymologic
- Gene Expression Regulation, Fungal
- Genes, Fungal
- Hydrogen-Ion Concentration
- Kinetics
- Molecular Sequence Data
- Multigene Family
- Phenotype
- RNA, Messenger
- Transcription, Genetic