Article
Host versus in vitro signals and intrastrain allelic differences in the expression of a Candida albicans virulence gene.
Molecular microbiology - 1 Jun 2002
Staib Peter, Kretschmar Marianne, Nichterlein Thomas, Hof Herbert, Morschhäuser Joachim
Abstract excerpt
The yeast Candida albicans is a harmless colonizer of mucosal surfaces in healthy people but can become a serious pathogen in immunocompromised patients, causing superficial as well as systemic infections. The evolution of gene families encoding pathogenicity-related functions, like adhesins and secreted aspartic proteinases (Saps), which are differentially induced by host signals at various stages of...
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